sin fights God

"I start by reminding you of what the bible says about the nature of sin. We use the word with a merely social meaning. We use it to signify certain types of behaviour acted out by one human being against another. This is a bad start because we are secularising a theological word whose meaning in scripture is always conceived and defined in terms of a wrong relationship to god. God is the reference point for defining sin, not other humans....
Sin is essentially the resolve... To play god and fight the real god. Sinners resolve to treat themselves as the centre of the universe... Sin wills that God should not be there. Sin plays God, sin fights God, and sin wishes that God didn't exist at all."

JI Packer, The necessity of the atonement.